REGIONAL NEAR-INFRARED SPECTROSCOPY (NIRS-liver) FOR ASSESSING LIVER GRAFT FUNCTION

Аннотация

Objective: To determine the correlation between regional oxygenation parameters of the liver graft using NIRS-liver and clinical-instrumental indicators in the early postoperative period following living donor liver transplantation. Materials and Methods. The study included 124 patients who underwent orthotopic liver transplantation from living donors. Graft oxygenation was monitored using near-infrared spectroscopy (NIRS-liver) for 48 hours. In addition, laboratory, hemodynamic, and ultrasound parameters were assessed. Results. Correlation analysis revealed a significant positive moderate association between hemoglobin levels and LSrO₂ (r=0.507; p<0.0001), as well as between hepatic artery blood flow velocity and LSrO₂ (r=0.328; p=0.002). A weak but statistically significant correlation was also observed between platelet count and LSrO₂ at the 48th hour of monitoring (r=0.401; p=0.0001), as well as between resistance index (RI) and LSrO₂ (r=0.350; p=0.001). Conclusion. The obtained results confirm the clinical relevance of NIRS-liver as a non-invasive method for assessing the functional status of the liver graft and for early detection of vascular complications.