CLINICAL LABORATORY CHANGES IN DIABETIC NEPHROPATHY

Аннотация

Objective: Assessment of the severity of the disease complicated by diabetic nephropathy based on laboratory parameters. Methods: The study was carried out on the basis of the Samarkand Regional General Hospital, Department of Nephrology. To achieve this goal, a retrospective study of patients' medical records was conducted. The number of patients with nephropathy in diabetes mellitus is 20. Of these, 12 (60%) are men, 8 (40%) are women. The average of the patients was 59.5 years. The results obtained: The main group included 20 patients with various courses of nephropathy. During clinical and laboratory examination, it turned out that in the general analysis of blood, the main changes are associated with red blood cells, which is manifested by a decrease in their number. The erythrocyte sedimentation rate (ESR) in all patients is sharply increased. When studying the biochemical parameters of the serum of patients, it was found that the residual nitrogen products are sharply increased, in all patients the level of cholesterol is moderately increased and the total protein is lowered. A general analysis of urine revealed protein in high concentrations, leukocytes and erythrocytes in insignificant amounts. Conclusions. In a significant part of the analyzed patients, changes in laboratory tests indicate that nephropathy is at the terminal stage of chronic renal failure.