PLASMAPHERESIS IN COMPLEX TREATMENT OF COMPLICATED FORMS OF CHRONIC PURULENT OTITIS MEDIA

Аннотация

A retrospective analysis of 145 case histories of patients with chronic suppurative otitis media (CSOM) with complications was conducted. CSOM with complications is a serious disease that requires a comprehensive approach to diagnosis and treatment. This pathology includes various local and intracranial complications that can significantly worsen the prognosis and quality of life of patients. The etiology of otogenic complications in CSOM is multifactorial and diverse. The main causes of them are bacteria, viruses and highly pathogenic microflora. As a result of the infectious process, as a protective reaction of the body, the indicators of endogenous intoxication increase, in particular the C-reactive protein indicator. Inflammatory processes in the body caused by viruses or bacteria can provoke moderate hypercoagulation, which leads to changes in the rheological properties of the blood. Increased levels of cholesterol and fibrinogen in blood plasma usually lead to deterioration of its rheological properties, which disrupts microcirculation and prevents full oxygenation of tissues and organs, which occurs in the pathogenesis of purulent otitis media with complications. In this article, we will discuss modern diagnostic methods and approaches to the treatment of chronic purulent otitis media with complications. The use of plasmapheresis helps to improve the rheological characteristics of the blood by reducing cholesterol and fibrinogen levels. In this regard, the inclusion of plasmapheresis in complex therapy seems justified, since it helps restore homeostasis.