CLINICAL FEATURES OF OSTEOARTHRITIS IN PATIENTS WITH UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA AND ITS RELATIONSHIP WITH MAGNESIUM LEVELS

Аннотация

In recent years, there has been increasing interest in the problem of undifferentiated connective tissue dysplasia (UCTD) due to the growing number of patients with this pathology. The aim of this study was to carry out comparative analysis of expression indicators of antibodies to collagen I of type and their interconnection with Mg2+ ions at patients of the undifferentiated connective tissue dysplasia (UCTD). 86 persons of them aged 15-25 (19.9±1.42) years with phenotypic signs of UCTD, have been studied. At patients against the background of NDST according to EhoKG it was revealed the prolapse of the mitral valve (PMV) with I and II degree of regurgitation, the small anomalies of heart (SAH), they noted decrease in level of ions of Mg 2 and increase in credits of autoantibodies to collagen I type. Dynamics of change of level of autoantibodies and also magnesium depending on weight of a clinical current of NDST can serve as method of assessment of progressing of pathological process and the prognosis of the disease.