THE IMPACT OF METABOLIC SYNDROME ON THE MORPHOFUNCTIONAL STATE OF THE ADRENAL GLANDS

Аннотация

This article examines the impact of metabolic syndrome (MS) on the morphofunctional state of the adrenal glands. An experimental study was conducted on laboratory outbred white rats in which MS was modeled by a high-fat and carbohydrate diet and physical inactivity. Macroscopic and histological analyses revealed an increase in the mass of the adrenal glands, hyperplasia of the cortical layer, changes in vascular architectonics and dystrophic processes in the medulla. The obtained results highlight the importance of early diagnosis and targeted therapy for adrenal dysfunction in MS.