OPTIMIZATION OF THERAPY FOR PATIENTS WITH PSORIASIS BASED ON CLINICAL, BIOCHEMICAL AND IMMUNOLOGICAL INDICATORS

Аннотация

Psoriasis is a chronic inflammatory skin disease characterized by keratinocyte hyperplasia and impaired immune response. The disease affects approximately 2-3% of the world's population and is associated with marked impairment of quality of life and significant health and social consequences ]20]. The presence of psoriasis in women significantly reduces their self-esteem and quality of life. The pathogenesis of psoriasis is a complex interaction of genetic, environmental, and immunologic factors. Understanding these mechanisms has become the basis for the development of new therapeutic approaches aimed at improving clinical outcomes