PROINFLAMMATORY AND ADIPOCYTE MARKERS AS INDICATORS OF MENSTRUAL CYCLE DISORDERS IN OVERWEIGHT ADOLESCENT GIRLS

Аннотация

Objective: to determine the serum levels of key adipokines and pro-inflammatory cytokines in overweight teenage girls to identify their role in the development of menstrual disorders. Material and methods. The study involved 50 teenage girls, of whom the main group included 25 overweight girls. The control group included 25 girls with normal body weight. Determination of serum levels of adipokines and proinflammatory cytokines was carried out by ELISA, in accordance with the manufacturer's recommendations. Results. Adipokine imbalances and elevated levels of proinflammatory cytokines were found to be associated with menstrual dysfunction in overweight adolescents. The studied indicators are significant predictors of menstrual disorders.